Some Hormonal Contraceptives Increase Acne

In a retrospective study published in the Journal of Drugs in Dermatology (June 2016), researchers David Lortscher, MD, et al, sought to examine the influence of different, commonly prescribed hormonal contraceptives on acne.

They evaluated the patient-reported effects on acne from 2,147 patients who were taking a hormonal contraceptive at the time of their initial consultation for acne...

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Some Hormonal Contraceptives Increase Acne

In a retrospective study published in the Journal of Drugs in Dermatology (...

Biomarkers and Hair Loss in Women

A study published online June 23 in the British Journal of Dermatology found...

A recent study found topical tranexamic acid (TA), a plasmin inhibitor, to be...

SENTÉ has announced the appointment of Virginia L. Vega, PhD, as vice president of...

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Creating Effective Newsletters
By Mara L. Shorr and Jay A. Shorr of Best Medical Business Solutions Each day, your patients’ email inboxes are flooded with e-newsletters and e-blasts craving their attention. Whether they come from daily deal sites, their favorite big box stores or their tried and true online retailers, the sheer...
Setting Expectations for Your Suppliers
By Carol and Rob Trow of Dermaconcepts There are few, if any, more problematic profit issues for aesthetic professionals, practice owners and managers than how to increase retail revenue for their practices. The challenges center on several endemic root causes, which I will discuss below. But it...
Some Hormonal Contraceptives Increase Acne

In a retrospective study published in the Journal of Drugs in Dermatology (June 2016), researchers David Lortscher, MD, et al, sought to examine the influence of different, commonly prescribed hormonal contraceptives on acne.

They evaluated the patient-reported effects on acne from 2,147 patients who were taking a hormonal contraceptive at the time of their initial consultation for acne: Each patient provided her assessment of how her contraceptive had affected her acne. The Kruskal-Wallis test and logistic regression analysis were used to compare patient-reported outcomes by contraceptive type.

The researchers found that depot injections, subdermal implants and hormonal intrauterine devices worsened acne on average, and were inferior to the vaginal ring and combined oral contraceptives (COCs; p ≤ 0.001 for all pairwise comparisons), which improved acne on average.

They also observed a hierarchy within the COC categories, based on the progestin component: drospirenone (most helpful) > norgestimate and desogestrel > levonorgestrel and norethindrone (p ≤ 0.035 for all pairwise comparisons). The presence of triphasic progestin dosage in COCs had a positive effect on acne (p = 0.005), while...

Biomarkers and Hair Loss in Women

A study published online June 23 in the British Journal of Dermatology found that low high-density lipoprotein (HDL) cholesterol and insulin-like growth factor 1 (IGF-1) were associated with a higher risk of hair loss in women.

Researchers investigated associations between markers of cardiovascular disease risk (e.g., serum lipid levels and hypertension) and aging (e.g., 25-hydroxyvitamin D and IGF) with hair loss in a random subgroup of 323 middle-aged women from the Leiden Longevity Study. The patients’ hair loss was graded by three assessors using the Sinclair scale; women with a mean score > 1.5 were classified as cases with hair loss.

Every 1 SD increase in HDL cholesterol was associated with a 0.65-times lower risk [95% confidence interval (CI); 0.46-0.91] of hair loss. For IGF-1 the risk was 0.68 times lower (95% CI; 0.48-0.97) per 1 SD increase, independent of the other studied variables. Women with both IGF-1 and HDL cholesterol levels below the medians of the study population had a 3.47-times higher risk (95% CI; 1.30-9.25) of having hair loss. The researchers noted that further studies would be required to infer causal relationships.

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Tranexamic Acid Effective for Melasma

A recent study found topical tranexamic acid (TA), a plasmin inhibitor, to be effective for treating melasma, with a possible mechanism of action being the suppression of Endothelin 1 (ET-1). Former studies have suggested that TA interferes with the interaction between melanocytes and keratinocytes and may reverse increased vasculature seen in melasma.

The study, published in Clinical and Experimental Dermatology (July 2016), enrolled 23 participants with melasma, who applied a 2% TA formulation to the whole face for 12 weeks. Clinical effects were evaluated using the modified Melasma Area and Severity Index (mMASI) and a chromameter. Skin biopsies were obtained from 10 participants to evaluate pigmentation, vascularity and the expression levels of possible paracrine factors contributing to the effect of TA.

The majority of subjects had mild melasma, with mMASI scores of < 5. The mMASI scores significantly improved in 22 of 23 participants after application. The L* (lightness) values were increased and the a* (red/green) values were decreased in both lesional and perilesional skin. Fontana-Masson staining showed a significant decrease in melanin content in the epidermis. The number of CD31-positive...

AAD Commends FDA for Indoor Tanning Restrictions

The American Academy of Dermatology (AAD) applauds the U.S. Food and Drug Administration (FDA) for proposing new regulations governing indoor tanning, including an age restriction for minors under the age of 18 as well as a risk-acknowledgement form that all adults must sign before using indoor tanning devices.


According to the AAD, statistics show that millions of people tan indoors annually and the risk of developing melanoma increases by 59% for individuals exposed to UV radiation from indoor tanning—the risk increases with each use. If the FDA’s proposed rule becomes final,... more »

ASDS Honored With 14 MarCom Awards

The American Society for Dermatologic Surgery (ASDS) and American Society for Dermatologic Surgery Association (ASDSA) were recognized with 14 awards—including three Platinums—in the 2015 MarCom Awards.


The MarCom Awards competition is administered and judged by the Association of Marketing and Communication Professionals, selecting winners “whose work serves as a benchmark for the industry.” The 2015 competition received about 6,500 entries representing more than a dozen countries.


The Platinum Award—MarCom’s top honor—was presented to ASDS in three categories: Currents... more »

Cellfina Available in US

Merz Aesthetics has begun commercial shipment of the Cellfina System, indicated for long-term improvement in the appearance of cellulite in the buttocks and thighs, to aesthetic practices in the U.S.


Cellfina combines proprietary technology with minimally invasive subcision to treat the primary structural cause of dimpled cellulite. Results of the procedure last at least two years—in clinical trials, patient satisfaction with their treatment results improved from 94% at one year to 96% at the two-year mark. The most common side effects reported were soreness, tenderness and bruising... more »