Antibiotic Resistance

Reviewing Antibiotic Resistance in Acne Treatment

Staphylococcus aureus

In an effort to provide guidance to prescribers and encourage further research on the risk of antibiotic resistance in acne treatment, JAMA Dermatology published a clinical evidence synopsis (online June 21, 2017). Brandon L. Adler, MD, et al, reviewed five clinical trials published in 1987-2002 and 2007-2008. They found evidence that the widespread use of bacteriostatic antibiotics (topical erythromycin and clindamycin and oral tetracyclines) may encourage the emergence of antibiotic-resistant strains of P acnes, via point mutations.